Skills

R

90%

Statistics

100%

Experience

 
 
 
 
 
July 2017 – Present
Massachusetts

Post Doctorate Associate

Broad Institute of MIT and Harvard

Responsibilities include:

  • Analysing
  • Modelling
  • Deploying
 
 
 
 
 
August 2012 – July 2017
Pennsylvania

Statistical Analyst

Penn State Health

Assisted in analyzing clinical and quality outcomes in the hosptial.
 
 
 
 
 
April 2011 – August 2012
Pennsylvania

Human Research Technologist

Penn State College of Medicine

Collected samples and managed data for studies on Acute Kidney Injury
 
 
 
 
 
August 2010 – August 2011
Pennsylvania

Math Teacher

Cornwall-Lebanon School District

Selected Publications

Background: Genetic interactions involving more than two loci have been thought to affect quantitatively inherited traits and diseases more pervasively than previously appreciated. However, the detection of such high-order interactions to chart a complete portrait of genetic architecture has not been well explored.
An Ultrahigh-Dimensional Mapping Model of High-order Epistatic Networks for Complex Traits, 2018

Knowledge about how changes in gene expression are encoded by expression quantitative trait loci (eQTLs) is a key to construct the genotype–phenotype map for complex traits or diseases. Traditional eQTL mapping is to associate one transcript with a single marker at a time, thereby limiting our inference about a complete picture of the genetic architecture of gene expression. Here, we implemented an ultrahigh-dimensional variable selection model to build a computing platform that can systematically scan main effects and interaction effects among all possible loci and identify a set of significant eQTLs modulating differentiation and function of gene expression. This platform, named iFORM/eQTL, was assembled by forward-selection-based procedures to tackle complex covariance structures of gene–gene interactions. iFORM/eQTL can particularly discern the role of cis-QTLs, trans-QTLs and their epistatic interactions in gene expression. Results from the reanalysis of a published genetic and genomic data set through iFORM/eQTL gain new discoveries on the genetic origin of gene expression differentiation in Caenorhabditis elegans, which could not be detected by a traditional one-locus/one-transcript analysis approach.
iFORM/eQTL: an ultrahigh-dimensional platform for inferring the global genetic architecture of gene transcripts, 2016

Accomplish­ments

Data Engineering, Big Data, and Machine Learning on Google Cloud Platform

Coursera

This five-course accelerated specialization is designed for data professionals who are responsible for designing, building, analyzing, and optimizing big data solutions. Through a combination of video lectures, quizzes, and hands-on labs, learners carried out serverless data analysis and productionize machine learning models. This specialization is designed to give learners a robust hands-on experience and is primarily labfocused.

Biological Diversity (Theories, Measures and Data sampling techniques)

Coursera

Blockchain for Business - An Introduction to Hyperledger Technologies

edX

Recent Publications

To study how genes function in a cellular and physiological process, a general procedure is to classify gene expression profiles into …

Background: Genetic interactions involving more than two loci have been thought to affect quantitatively inherited traits and diseases …

The coordination of shoots and roots is critical for plants to adapt to changing environments by fine‐tuning energy production in …

Epigenetic reprogramming is thought to play a critical role in maintaining the normal development of embryos. How the methylation state …

Heterophylly, i.e. morphological changes in leaves along the axis of an individual plant, is regarded as a strategy used by plants to …

Knowledge about how changes in gene expression are encoded by expression quantitative trait loci (eQTLs) is a key to construct the …

Recent & Upcoming Talks

Recent Posts

R Markdown This is an R Markdown document. Markdown is a simple formatting syntax for authoring HTML, PDF, and MS Word documents. For …

Create a beautifully simple website or blog in under 10 minutes.

R Markdown This is an R Markdown document. Markdown is a simple formatting syntax for authoring HTML, PDF, and MS Word documents. For …

Projects

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External Project

Workshop course on the analysis on single cell RNA-seq data.

Teaching

Contact